PKPDsim

PKPDsim is a library for numerical integration of ODE systems, in particular pharmacokinetic-pharmacodynamic (PK-PD) mixed-effects models.

Installation

The development version of PKPDsim always has the most up-to-date improvements and bug fixes. We aim to release PKPDsim on CRAN at least once a year, depending on the number and impact of updates made to the development version.

The CRAN version of PKPDsim can be installed using:

install.packages("PKPDsim")

The development version of PKPDsim can be installed using:

devtools::install_github("InsightRX/PKPDsim")

A number of models from the literature have been made available for use in PKPD simulations. To see which models are available for installation, run:

available_default_literature_models()

You can install these models as packages using the following commands:

# To install a single model:
install_default_literature_model("pk_busulfan_mccune")
# To install all supplied models:
install_default_literature_model("all")

Contributing

We welcome input from the community:

Disclaimer

The functionality in this R package is provided “as is”. While its authors adhere to software development best practices, the software may still contain unintended errors.

InsightRX Inc. and the authors of this package can not be held liable for any damages resulting from any use of this software. By the use of this software package, the user waives all warranties, expressed or implied, including any warranties to the accuracy, quality or suitability of InsightRX for any particular purpose, either medical or non-medical.

© InsightRX logo